Name of this trial: Destiny-BTC What type of cancer is this for? Biliary Tract Cancer Who is this trial for? First line for locally advanced or metastatic HER2 expressing biliary tract cancer What biomarkers are involved? HER2 positive (expressing) What is the National Clinical Trial #? NCT06467357 Brief summary of this trial: Phase 3
Archives: Clinical Trials
Breast
Name of this trial: INAVO123 What type of cancer is this for? Breast Cancer Who is this trial for? Patients with locally advanced or metastatic breast cancer. What biomarkers are involved? PIK3CA-positive, ER+, HER2- What is the National Clinical Trial #? NCT06790693 Brief summary of this trial: This is a blinded trial that consists of
Colorectal
Name of this trial: Origami-2 What type of cancer is this for? Colorectal Cancer Who is this trial for? Patients with Unresectable or Metastatic Left-sided Colorectal Cancer What biomarkers are involved? KRAS/NRAS and BRAF Wild-type What is the National Clinical Trial #? NCT06662786 Brief summary of this trial: Randomized, Open-label Phase 3 Study of Amivantamab
Esophageal
NAME: GEMINI GASTRIC What type of cancer is this for? Stomach and where the stomach and esophagus join together Phase: II Who is this trial for: Men and women who have stomach cancer, or cancer where the stomach and esophagus meet, that cannot be removed or has spread to other parts of the body What
Gallbladder
NAME: PanTumor3- Biliary Tree What type of cancer is this for: Liver, gallbladder, bile ducts Phase: II Who is this trial for: Men and women who have cancer in their biliary tract: liver and/or gallbladder and/or bile ducts that has spread to other parts of the body and cannot be taken out. What biomarkers are
Gastric
Name of this trial: Gemini-PeriOp What type of cancer is this for? Gastroesophageal Cancer Who is this trial for? Patients with locally advanced, resectable gastroesophageal cancer What biomarkers are involved? Multiple cohorts include CLDN18.2, HER2 positive, and all-comers What is the National Clinical Trial #? NCT07069712 Brief summary of this trial: Open-Label, Multi-Drug, Multi-Center, Phase
Hematology
Kidney
Name of this trial: Artemide-HCC01 What type of cancer is this for? Advanced Hepatocellular Cancer Who is this trial for? Patients who have advanced kidney cancer that have not had prior treatment in advanced setting. What biomarkers are involved? Central PD-L1 testing, however positivity not dependent on inclusivity What is the National Clinical Trial #?
Leukemia
Name of this trial: BGB-11417-303/CLL-RR1 What type of cancer is this for? Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Who is this trial for? Relapsed and/or Refractory What biomarkers are involved? CLL Cytogenics (eg, del(17p), del(11q), del(13q), and trisomy 12), complex karyotype, and the mutational status of relevant genes such as IGHV, TP53, and other CLL-related prognosis
Liver
NAME: PanTumor3- Biliary Tree What type of cancer is this for: Liver, gallbladder, bile ducts Phase: II Who is this trial for: Men and women who have cancer in their biliary tract: liver and/or gallbladder and/or bile ducts that has spread to other parts of the body and cannot be taken out. What biomarkers are