Comprehensive Sickle Cell Care at The Cancer & Hematology Centers
At The Cancer & Hematology Centers (CHC), we are committed to care that is equitable, accessible, and built around the sickle cell warrior — not just the diagnosis. We work to close the gaps that too often stand between patients and excellent care, and to keep you at the center of every decision.
A Recognized Comprehensive Sickle Cell Center. The Cancer & Hematology Centers is recognized by the National Alliance of Sickle Cell Centers (NASCC) as a Comprehensive Sickle Cell Center — part of a national network of programs committed to meeting the highest standards of specialized sickle cell care.
Specialized Sickle Cell Care at CHC
CHC is proud to offer dedicated sickle cell care led by Dr. Luke Eastburg, who oversees all sickle cell patients across our practice.
Dr. Eastburg is triple board certified in internal medicine, pediatrics, and hematology — a combination of training that is especially valuable in sickle cell disease, where care must span childhood, the transition to adulthood, and the full complexity of a lifelong blood disorder. He works closely with each patient to develop individualized treatment plans, monitor long-term health, and provide access to the latest therapies and advancements in care.
Patients benefit from:
- Coordinated, expert-led care from a sickle cell specialist
- A supporting team of advanced practice providers and nurses experienced in sickle cell care
- Access to advanced treatment options and clinical trials
- Compassionate support for both patients and families
Treating Sickle Cell Disease
We provide lifelong care focused on easing symptoms, preventing complications, and protecting quality of life. Your personalized plan may include:
- Medications to manage pain and reduce sickling — such as hydroxyurea (Droxia, Hydrea), L-glutamine (Endari), and crizanlizumab (Adakveo)
- Blood transfusion or exchange transfusion therapy
- Individualized Care Plan (ICP) for a sickle cell pain crises — a personalized protocol that outlines the specific pain medications, doses, and comfort measures (such as fluids, heat, rest, and breathing exercises) that work best for that individual patient, so that treatment can begin quickly and effectively whether managing pain at home, infusion clinic, or emergency department
- Chelation therapy to treat iron overload
- For some people with severe disease, a stem cell transplant may offer a cure. Gene therapies are also being developed that may one day cure sickle cell disease.
Understanding Sickle Cell Disease
What Is Sickle Cell Disease?
Sickle cell disease (SCD) is an inherited blood disorder that affects red blood cells. Instead of being round and flexible, the cells become rigid and shaped like a crescent, or “sickle.” These abnormal cells can block blood flow, leading to pain, infections, and other serious complications throughout the body.
Who Gets Sickle Cell Disease?
Sickle cell disease is a genetic condition passed down from parents. It most commonly affects individuals of:
- African or African American descent
- Hispanic or Latino backgrounds
- Middle Eastern, Mediterranean, or South Asian heritage
A person must inherit the sickle cell gene from both parents to have the disease. Those who inherit only one gene have “sickle cell trait.” They may not experience symptoms but can pass the gene to their children.
Symptoms & Complications
SCD can affect any major organ. The liver, heart, kidneys, gallbladder, eyes, bones, and joints can all be damaged. They suffer damage from the abnormal function of the sickle cells and their inability to flow through the small blood vessels correctly.
Problems may include:
- Anemia
- Pain crisis, or sickle crisis
- Acute chest syndrome causing lung damage.
- Leg ulcers or serious sores
- Bone tissue damage or death
- Early gallstones
- Kidney damage and loss of body water in the urine
- Eye damage
- Multiple organ failure
- Stroke
- Increased infections and fever
- Blood clots
- Painful swelling of hands and feet
Where can I learn more about sickle cell disease?
- We encourage patients to learn about their disease and stay up to date on treatments and research studies. Your sickle cell doctor is always willing to answer questions or help you understand more clearly.
- Trusted websites for Sickle Cell Information
You Are Not Alone
At CHC, we believe in delivering more than treatment — we provide help, hope, and healing. If you or a loved one is living with sickle cell disease, our team is here to support you every step of the way.
Request an appointment today to connect with our sickle cell care team.