Name of this trial: CODEBREAK 301
What type of cancer is this for? COLON
Phase of this trial? Phase III
Who is this trial for? Men and women with colon cancer that has spread to other parts of the body.
What biomarkers are involved? Your cancer must have a KRAS P.G12C mutation.
What is the National Clinical Trial# NCT04303780
Brief summary of trial: This trial is randomized 1:1 to either Sotorarsib+Panitumumab+FOLFIRI (standard chemo regimen) vs. standard of care chemotherapy regimens FOLFOX or FOLFIRI +/- Avastin. The study is investigating which of these treatment plans shows longer overall survival and progression-free survival in metastatic colon cancer patients.
Need to know: You may have had treatment for your colon cancer before it spread, but now that it has spread, this has to be the first treatment you receive for it.
Where is this trial available?: The Cancer & Hematology Centers and other sites nationwide, please click on link above to review.
For more information, please call 616-975-3065 or email [email protected]
Name of this trial: CARDIFF-004
What type of cancer is this for? COLORECTAL cancer
Phase of this trial? Phase II
Who is this trial for? Men and Women with colorectal cancer that has spread but they have never had treatment for their disease.
What biomarkers are involved? Your cancer must have a KRAS or NRAS mutation.
What is the National Clinical Trial# NCT06106308
Brief summary of trial: This trial looks at how well two different doses of the study drug (onvansertib) work when combined with two different chemotherapy plans.
Need to know: You may have had treatment for your colorectal cancer before it spread, but now that it has spread, this has to be the first treatment you receive for it.
Where is this trial available?: The Cancer & Hematology Centers and other sites nationwide, please click on link above to review.
For more information, please call 616-975-3065 or email [email protected]