NAME: Carmen-LC03
What type of cancer is this for? Non-small-cell lung cancer
Phase: III
Who is this trial for? Men and women with non-squamous, non-small-cell lung cancer who have had treatment (chemo) before.
What biomarkers are involved? Your tumors must be CEACAM5 positive.
What is National Clinical Trial#? NCT04154956
Brief summary of trial: This trial is looking at which drug works best to keep your disease from growing for the longest period of time.
Need to know: You must have received either Cisplatin or Carboplatin chemotherapy and an “immune checkpoint inhibitor” in your past treatments.
Where is this trial available? The Cancer & Hematology Centers
For more information, please call 616-975-3065 or email clinicaltrials@chcwm.com
Name: GENMAB
What type of cancer is this for? Non-small-cell lung cancer
Phase: II
Who is this trial for? Men and women who have non-small-cell lung cancer that has spread to other parts of their body.
What biomarkers are involved? Your tumor must have PD-L1 expression in greater than 1% of your tumor cells.
What is National Clinical Trial #? NCT05117242
Brief summary of trial: This study compares how well their new drug works (shrinks the tumors) by itself vs. giving it with “pembrolizumab”.
Need to know: You need to have had the standard treatment (chemo) and an “immune checkpoint inhibitor” as prior treatment.
Where is this trial available? The Cancer & Hematology Centers
For more information, please call 616-975-3065 or email clinicaltrials@chcwm.com
Name: IMFORTE
What type of cancer is this for? Small-cell lung cancer
Phase: III
Who is this trial for? Men and women with extensive stage small cell lung cancer who have had a specific chemo plan before.
What biomarkers are involved? None
What is National Clinical Trial #? NCT05091567
Brief summary of trial: This trial is looking at whether Lurbinectedin works better alone, or if it works better when you add Atezolizumab.
Need to know: You need to have had four cycles of a certain chemotherapy plan: Carboplatin, Etoposide and Atezolizumab
Where is this trial available? The Cancer & Hematology Centers
For more information, please call 616-975-3065 or email clinicaltrials@chcwm.com
Name: Pacific-9
What kind of cancer is this for? Non-small cell lung cancer
Phase: III
Who is this trial for? Men and women with locally advanced (Stage III) non-small cell lung cancer that cannot be removed by a doctor.
What biomarkers are involved? PD-L1, EGFR and ALK
What is National Clinical Trial #? NCT05221840
Brief summary of trial: This study is looking to prove that durvalumab and oleclumab work better than durvalumab and a placebo (harmless medication) do.
Need to know: You must have had a chemo plan that included either Cisplatin or Carboplatin, along with radiation at the same time you were getting chemotherapy. Your disease cannot have grown any bigger since chemo and radiation finished.
Where is this trial available? The Cancer & Hematology Centers
For more information, please call 616-975-3065 or email clinicaltrials@chcwm.com